Andreas Mandelis (born 22 June 1952), is a professor and researcher in the department of Mechanical and Industrial Engineering at the University of Toronto and director of the Centre for Advanced Diffusion-Wave and Photoacoustic Technologies (CADIPT). He is an internationally recognized expert in photoacoustics, thermophotonics, and diffusion-wave sciences. His research encompasses the non-destructive evaluation of materials with industrial and biomedical applications. He is considered a pioneer in the fields of diffusion-wave, photothermal and photoacoustic sciences and related technologies. He is the inventor of a photothermal imaging radar which can detect tooth decay at an early stage.
He and his research group have pioneered 18 advanced laser instrumentation technologies and analytical measurement methodologies, including photothermal coherence tomographies for non-invasive bone osteoporosis monitoring, and the photoacoustic radar for non-invasive early cancer imaging. Globally speaking, these technologies hold the promise of the earliest possibility of diagnosis in a broad range of otherwise invisible, subsurface inhomogeneities in all matter, from potentially catastrophic automotive cracks and aerospace gear defects, to semiconductor device fabrication electronic defect quality control and device performance assessment, to subsurface dental enamel and dentin demineralization caries, bone osteoporosis, and deep and shallow tissue tumors and biomedical health risks such as the onset of breast cancer and diabetic blood glucose concentration monitoring.
Early life and education
Mandelis was born in Corfu, Greece. In 1974, he obtained his Bachelor of Science degree in Physics from Yale University. Subsequently in 1979 he graduated from Princeton University obtaining his MA, MSE, and Ph.D. degrees from the Applied Physics and Materials Laboratory in the Department of Mechanical and Aerospace Engineering at Princeton.
After graduating from Princeton, Mandelis worked as a researcher at Bell-Northern Research Labs in Ottawa from 1980-1981. He has written and co-authored over 370 papers which have appeared in peer-reviewed journals and about 200 papers in scientific and technical proceedings.
He is the editor-in-chief of the book series "Progress in Photothermal and Photoacoustic Science and Technology" which is published by the Society for Optical Engineering (SPIE). He is the director of the Center for Advanced Diffusion-Wave and Photoacoustic Technologies (CADIPT) at the University of Toronto. He has appeared as the guest editor in special publications in the area of photoacoustic, photothermal and diffusion-wave phenomena.
He is editor-in-chief of the Springer International Journal of Thermophysics. He is an associate editor for the Americal Institute of Physics (AIP) Journals Review of Scientific Instruments and the Journal of Applied Physics. He is also a member in the editorial and advisory boards of the SPIE Journal of Biomedical Optics, and Optics Letters of the Optical Society of America, responsible for the areas of photothermal imaging, dental optics, and photoacoustic tomography. He is contributing editor for Physics Today, the flagship magazine of the American Institute of Physics.
Mandelis is a Fellow of the Royal Society of Canada, a Fellow of the American Physical Society, a Fellow of the SPIE, a Fellow of the ASME, Fellow of the Canadian Academy of Engineering, and a Fellow of the American Association for the Advancement of Science. He is the President of the International Photoacoustic and Photothermal Association (IPPA).
He is an internationally recognized expert in applied photonics, imaging, optoelectronics, materials science and biophotonics. He is considered a pioneer in the fields of diffusion-wave, photothermal and photoacoustic sciences and related technologies and his research is recognized as having helped define and develop these areas. He also pioneered the Thermal-Wave Resonant Cavity, which has applications in the fields of molecular thermophysics, kinetic theory and the infrared emissivity of fluids. Mandelis has created the field of dental photonic engineering, the non-destructive semiconductor inspection techniques of photocarrier radiometry. and lock-in carrierography, as well as several non-invasive laser-based biophotonic methodologies for early cancer tumor and dental demineralization caries imaging.
Andreas Mandelis currently works as a full professor at the Department of Mechanical and Industrial Engineering at the University of Toronto which he joined in 1981. He is also a professor at the Electrical and Computer Engineering department and the Institute of Biomaterials and Biomedical Engineering at the same university and a Thousand Talents Professor at the University of Electronic Science and Technology, Chengdu, China. His current research in the field of biomaterials and biomedical engineering involves establishing the fields of biophotonics and biophotoacoustics as they apply to biological tissues.
Mandelis is co-founder and chief technology officer of Quantum Dental Technologies and he is the recipient of the 2012 CAP-INO Medal for Outstanding Achievement in Applied Photonics. The company's device, named the 'Canary System', uses laser pulses to detect tooth decay and is used as a non-invasive alternative to traditional methods including x-rays. The machine detects tooth demineralization at an early stage so that the damage can be repaired using remineralizing compounds and avoid the use of drils. He has also founded two more Ontario, Canada, companies for marketing intellectual property products of his group’s diversified research in several fields: a 2001 University of Toronto spin-off company “Photo-Thermal Diagnostics, Inc.”, which was expanded into “Diffusion-Wave Diagnostic Technologies, Inc.” in 2009. The companies market quality control instrumentation for semiconductor materials and devices through photocarrier radiometry and lock-in carrierography imaging technology, and non-destructive imaging for industrial engineering materials technology based on his thermal-wave radar method which enhances subsurface defect imaging contrast.
Memberships and awards
Alexander von Humboldt Research Award, Humboldt Foundation, Germany.
Member of K7 (ASME) International Committee on Thermophysics.
Associate Editor, AIP Review of Scientific Instruments.
2004 New Pioneers Award in Science and Technology, Skills for Change, City of Toronto.
Founder and Chair of SPIE BiOS (Photonics West) Conference on “Optics in Bone Biology and Diagnostics”.
Inaugural (2007) Premier’s Discovery Award in Science and Engineering, Ministry of Research and Innovation, Ontario.
Canada Research Chair (Tier 1) in Diffusion-Wave Sciences and Technologies (2008-2015). Reappointed Canada Research Chair in Diffusion-Wave and Photoacoustic Sciences and Technologies (2015-2022).
2009 Senior Prize of the International Photoacoustic and Photothermal Association.
2009 Canadian Association of Physicists (CAP) Medal for Outstanding Achievement in Industrial and Applied Physics.
2009 Yeram S. Touloukian Award in Thermophysics, ASME.
Killam Research Fellowship.
2012 Joseph F. Keithley Award for Advances in Measurement Science. Citation: "For seminal contributions to the development of new experimental techniques based on photothermal science, and the application of these techniques to a variety of real-world problems."
2012 Canadian Association of Physicists (CAP)-INO Medal for Outstanding Achievement in Applied Photonics.
Founder of biennial Mediterranean International Workshop on Photoacoustic & Photothermal Phenomena (Professor Roberto Li Voti, University of Rome, co-founder), Center Ettore Majorana in Erice (Sicily, Italy).
2013 University of Toronto Inventor of the Year Award.
2014 Killam Prize
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